Topokine Therapeutics is a clinical-stage biotechnology company developing topical medications for non-invasive contouring of the face and body. The company’s lead program, XAF5 Gel, is a topical adipomodulatory product in Phase 2 clinical development for local reduction of excess submental fat (“double chin”) and other indications. Topokine’s pipeline also includes XOPH5 Ointment to treat steatoblepharon (“eye bags”) and TAT4, a topical “filler” therapy to increase local tissue volume.